Bulbus Allii Sativi
Investigation of Allium sativum’s Protective Effect on Ovarian Reserve in an Experimental Ovarian Injury Model
We aimed to evaluate the effects of detorsion and Allium sativum (garlic oil) treatment on the ovarian reserve in an ovarian torsion model. Ovarian torsion may lead to loss of ovarian tissue and infertility. It is an experimental rat study that was carried out on 16 sets of ovaries each, one for treatment group and a control group. In the control group, the procedure involved only the surgically opening and closing the abdomen. Bilateral adnexal torsion/detorsion was performed after a 3-hour ischemia period for the detorsion-only group. The detorsion + Allium sativum group received a 5 ml/kg dose of Allium sativum intraperitoneally, 2 hours before surgery. After the second surgery, removed ovarian samples were evaluated for follicle counts, damage scores and other parameters. Primordial, preantral, small antral and large antral follicle counts were significantly higher in the detorsion + Allium sativum group. Degeneration, congestion, hemorrhage ,inflammation and total damage scores were significantly elevated in the detorsion only group compared to those for the detorsion + Allium sativum group. Finally, there was a significant correlation between AMH alterations and postoperative, preantral follicle count (p<0.05). As a conclusion detorsion + Allium sativum treatment may be effective in protecting the ovarian reserve after torsion. KEY WORDS: Anti-Müllerian hormone; Detorsion; Allium sativum; Ovarian reserve; Oxidative stress><0.05). As a conclusion detorsion + Allium sativum treatment may be effective in protecting the ovarian reserve after torsion.
KEY WORDS: Anti-Müllerian hormone; Detorsion; Allium sativum; Ovarian reserve; Oxidative stress.
Antibacterial Effect of Ethanolic Extract of Allium sativum on Biofilm Forming Staphylococcus aureus which Cause Folliculitis
This study included isolation and identification of Staphylococcus aureus from folliculitis patients then detection the bacterial ability for biofilm formation, because biofilm play very important role in pathogenicity and antibiotics resistance of bacteria. Fifty specimens have been collected, 47 (94%) specimens collected by swabbing gave positive culture and 3 (6%) specimens gave negative culture. After Gram 44 (93.6%) isolates were Gram positive bacteria and 3 (6.4%) isolates were Gram negative bacteria when identification of positive and negative bacterial isolates has been completed the results showed that 2 (4.3%) isolates were Pseudomonas sp., 1 (2.1%) isolates was Klebsiiela sp. and 44 (93.6%) isolates were S. aureus. Thirty nine (88.6%) isolates of S. aureus produced biofilm and only 5 (11.4%) isolates not produced biofilm although isolates obtained from folliculitis patients and reflected resistance to antibiotics. Ciprofloxacin reflect high efficiency against S. aureus with inhibition zone (26mm) while ethanolic extract of locally garlic which showed high inhibitive ability against S. aureus with inhibition zone (28mm).
More information: https://www.ijcmas.com/7-1-2018/Shatha%20Al%20Bayati.pdf