• Clinical data 90%
  • Efficacy 80%
  • Security 90%
  • Toxicity 10%

Synonyms

Hibiscus sabdariffa L.

Major chemical constituents

It has a high content of organic acids (15-30%), among which citric acid, malic acid, tartaric acid and the lactone of the acid (+) – alohidroxicítrico, known as hibíscico acid, which is characteristic of the drug. The RFE prescribes a minimum of 13.5% acids (expressed as citric acid) for the drug.

The characteristic red color of the drug is due to anthocyanins (1.5%): 3-O-sambubiosil-delphinidin (hibiscin), 3-O-glucosyl-delphinidin, delphinidin, 3-O-sambubiosyl-cyanidin and 3- O-ß-D-glucopyranosyl-cyanidin.

It contains other polyphenols, such as flavonoids (quercetin, myricetin, hibiscetin, hibiscitrin and 3-O-glucosyl-gosipetina) and phenolic acids (protocatecholic, o-coumaric, p-coumaric and ferulic acids).

It also contains mucilaginous polysaccharides and pectins, among which a ramnogalacturonan, accompanied, to a lesser extent, by an arabinogalactan and an arabinano.

Other components are: traces of essential oil (with eugenol) and phytosterols.

Medicinal uses of Hibiscus sabdariffa

In 1998, the French Agency for Medicines approved the following allegations: for functional asthenias and to facilitate weight loss.

Several clinical studies have shown antihypertensive activity, by inhibition of the angiotensin-converting enzyme (ACE), and moderately lipid-lowering, which confirm the results of laboratory tests in animals. More studies, methodologically well done, would be necessary to corroborate these indications.

Pharmacology

Due to its organoleptic characteristics, the hibiscus flower is used mainly for the preparation of caffeine-free refreshing beverages, and it is frequently used as a flavor corrector or as an excipient to improve the appearance in mixtures of drugs for infusion.

Popularly, Hibiscus sabdariffa has been used as an appetite stimulant, mild laxative, diuretic, in colds and catarrhs ​​of the upper respiratory tract, and in circulatory disorders. In the countries of origin (tropical and subtropical zones of Africa, America and Asia), the infusion constitutes a social drink and is attributed diuretic, spasmolytic, antibacterial, cholagogue and even anthelmintic properties.

Some results obtained in animals and / or in vitro models, which show that the extracts of the drug have antioxidant and hepatoprotective activity. This activity has been related to anthocyanins and protocatechic acid, a substance that, in addition, has shown tumor antipyro- mous activity and induces apoptosis in human leukemic cells.

Contraindications

They have not been described.

Side effects

They have not been described.

More information: https://www.fitoterapia.net/vademecum/plantas/index.html?planta=309&tipo_nombre=2

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