• Clinical data 90%
  • Efficacy 80%
  • Security 80%
  • Toxicity 20%

Synonyms

Quassia amara

General appearance

Tree Tree 15 to 30 m high. Its erect trunk, up to 1 m in diameter, is covered with a thick, fluffy and grayish crust. The leaves are alternate, unevenly pinnate, with opposite leaves and oblong, acuminate, winged and uneven at the base. The small flowers, pale yellow or pinkish green, appear in October and November.

The fruit is composed of three drupes the size of a pea, bright, black, solitary and globose.

Major chemical constituents

A significant number of quasinoids have been isolated and identified in their wood and bark, some of them glycosylated: quasine, 1-α-O-methylquasin, 1-dihydro-α-hydroxyquasin, 18-hydroxyquasine, 14,15-dehydroquasin, 11 -dihydro-12-norneoquasin, neoquasin, 16-α-O-methylneoquasin, quasialactol, nigakilactone A, 11-α-O- (β-D-glucopyranosyl) -16-α-O-methylneoquasin, parain, 1-hydroxy 12-α-hydroxyparaine, 12-α-hydroxy-13,18-dehydroparaine, 12-dihydro-α-hydroxyparaine, 11-α-acetylparaine and isoparain.

Quassinoid concentration in the bark and Quassia wood will depend on the exposure of the plant to the sun as well as age. Quasine content is higher in specimens from rainforests or in shade conditions, and is higher when the diameter (age) of the branches is higher; On the other hand, the proportion of neoquasin, the second most abundant quasinoid in Quassia amara, seems to be higher in individuals exposed to the sun, also increasing with age.

In the fruits, flowers and leaves of Quassia amara, quasinoid quasine has been isolated and identified.

Medicinal uses of Quassia amara

It is useful for lack of appetite or difficult digestion due to gastric and intestinal atony, and cases in which it stimulates the secretion of digestive juices and favors the functioning of the gallbladder.

It is indicated in dyspepsia, constipation, digestive atony and liver congestion.

Quasia is not very toxic, however it is much higher on invertebrates, which is why it has been used as an antiparasitic agent and in the treatment of intestinal worm infections, especially pinworms.

Pharmacology

Between the medicinal uses, they are attributed to him: anti-pirético, appetizer, diuretic and stimulant of the gastrointestinal system.

Some studies show that it has anti-leukemic, anti-inflammatory, anti-viral, anti-malaric, amoebicidal activity and insecticidal properties.

Precautions

The use of cuasia is formally contraindicated during pregnancy, due to its contracting action on smooth muscle fibers.

More information: http://redsa.com.mx/descargas/fichastecnicas/cuasia.pdf

http://digital.csic.es/bitstream/10261/23084/1/BLACPMA_2008.pdf

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