Does Rhodiola Rosea Possess Ergogenic Properties?
Rhodiola rosea is an herb purported to possess adaptogenic and ergogenic properties and has recently been the subject of increased interest. The purpose of this article was to review and summarize recent investigations of the potential performance-enhancing properties of Rhodiola rosea. Such studies have generated equivocal results. Several investigations conducted in Eastern Europe have indicated that Rhodiola rosea ingestion may produce such positive effects as improved cognitive function and reduced mental fatigue. Other research from this region has illustrated enhanced endurance exercise performance in both humans and rats. Studies conducted in Western Europe and in North America have indicated that Rhodiola rosea may possess substantial antioxidant properties but have produced mixed results when attempting to demonstrate an ergogenic effect during exercise in humans.
Key Words: functional performance, exercise performance, phytomedicine, adaptogen
The impact of Rhodiola rosea on the gut microbial community of Drosophila melanogaster
Background: The root extract of Rhodiola rosea has historically been used in Europe and Asia as an adaptogen, and similar to ginseng and Shisandra, shown to display numerous health benefts in humans, such as decreasing fatigue and anxiety while improving mood, memory, and stamina. A similar extract in the Rhodiola family, Rhodiola crenulata, has previously been shown to confer positive efects on the gut homeostasis of the fruit fy, Drosophila melanogaster. Although, Rhodiola. rosea has been shown to extend lifespan of many organisms such as fruit fies, worms and yeast, its antiaging mechanism remains uncertain. Using D. melanogaster as our model system, the purpose of this work was to examine whether the anti-aging properties of Rhodiola rosea are due to its impact on the microbial composition of the fy gut.
Results: Rhodiola rosea treatment signifcantly increased the abundance of Acetobacter, while subsequently decreasing the abundance of Lactobacillales of the fy gut at 10 and 40 days of age. Additionally, supplementation of the extract decreased the total culturable bacterial load of the fy gut, while increasing the overall quantifable bacterial load. The extract did not display any antimicrobial activity when disk difusion tests were performed on bacteria belonging to Microbacterium, Bacillus, and Lactococcus.
Conclusions: Under standard and conventional rearing conditions, supplementation of R. rosea signifcantly alters the microbial community of the fy gut, but without any general antibacterial activity. Further studies should investigate whether R. rosea impacts the gut immunity across multiple animal models and ages.
Keywords: Drosophila melanogaster, Rhodiola rosea, Acetobacter pomorum, Lactobacillus plantarum, Bacterial load, Herbal extracts, Colony forming units, Quantitative RT-PCR, Disk difusion, 16S rRNA gene sequencing